Clin Osteol 2022; 27(1): 36-39

Chondroblastoma of the femur a benign tumor with potentially serious consequences: a case reportCase reports

Rendek Pavol1, Kokavec Milan1, Chládek Petr2
1 Ortopedická klinika LF UK a NÚDCH, Bratislava
2 Ortopedické oddělení, Vršovická zdravotní a. s., Praha

Chondroblastoma is a rare benign bone tumor, most often located in an epiphysis. It represents about 1 % of all benign bone tumors. Chondroblastoma is typical for young patients and occurs most often in the second decade of life. Clinical presentation consists of pain and restriction of movement in the affected joint. Histology shows a benign type of tumor, which can however grow aggressively and destroy its surroundings (spongiosa, cortical bone and joint cartilage) and expand into the joint cavity. Tumor cells produce cytokines, which are responsible for inflammatory processes occurring around the tumor such as bone edema or prominent synovitis in case of intraarticular growth. In 20 % of cases, we see a relapse despite treatment. In this article we present the case of a 15-year-old boy with a proximal femur chondroblastoma. After the initial biopsy, the tumor was treated surgically via surgical hip dislocation, which allows treatment of the femoral head without compromising nutritional blood vessels. After a radical excochleation and local chemoproteolysis, the defect was filled with partially resorbable bone cement. The patient has been monitored for a year now with a good clinical and radiological outcome.

Keywords: chondroblastoma; proximal femur; surgical hip dislocation

Received: January 18, 2022; Accepted: March 10, 2022; Published: June 11, 2022  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Rendek P, Kokavec M, Chládek P. Chondroblastoma of the femur a benign tumor with potentially serious consequences: a case report. Clinical Osteology. 2022;27(1):36-39.
Download citation

References

  1. 1. Kurt AM, Unni KK, Sim FH et al. Chondroblastoma of bone. Hum P athol 1 989; 2 0(10): 9 65-976. Dostupné z DOI: < http://dx.doi.org/10.1016/0046-8177(89)90268-2>.
  2. 2. Xu H, Nugent D, Monforte HL et al. Chondroblastoma of bone in the extremities: a multicenter retrospective study. J Bone Joint Surg Am 2015; 9 7(11): 9 25-931. Dostupné z DOI: < http://dx.doi.org/10.2106/JBJS.N.00992>.
  3. 3. Bloem JL, Mulder JD. Chondroblastoma: a clinical and radiological study of 104 cases. Skeletal Radiol 1985; 14(1): 1-9. Dostupné z DOI: <http://dx.doi.org/10.1007/BF00361187>.
  4. 4. de Silva MVC, Reid R. Chondroblastoma: varied histological appearance, potential diagnostic pitfalls, and clinicopathologic features associated with local recurrence. Ann Diagn Pathol 2003; 7(4): 205-213. Dostupné z DOI: <http://dx.doi.org/10.1016/s1092-9134(03)00048-0>.
  5. 5. Oxtoby JW, Davies AM. MRI characteristics of chondroblastoma. Clin Radiol 1996; 51(1): 2 2-26. Dostupné z DOI: <http://dx.doi.org/10.1016/s0009-9260(96)80213-3>.
  6. 6. Uchikawa C, Shinozaki T, Nakajima T et al. Cytokine Synthesis by Chondroblastoma: Relation to Local Inflammation. J Orthop Surg (Hong Kong) 2009; 17(1): 56-61. Dostupné z DOI: <http://dx.doi.org/10.1177/230949900901700113>.
  7. 7. Chen W, DiFrancesco LM. Chondroblastoma: An Update. Arch Pathol Lab Med 2017; 141(6): 867-871. Dostupné z DOI: <http://dx.doi.org/.5858/arpa.2016-0281-RS>.
  8. 8. Lin PP, Thenappan, Arun BS et al. Treatment and Prognosis of Chondroblastoma. C lin O rthop R elat R es 2 005; 4 38 : 1 03-109. Dostupné z DOI: <http://dx.doi.org/10.1097/01.blo.0000179591.72844.c3>.
  9. 9. Turcotte RE, Kurt A-M, Sim FH et al. Chondroblastoma. Hum Pathol 1993; 24(9): 944-949. Dostupné z DOI: <http://dx.doi.org/10.1016/0046-8177(93)90107-r>.




Clinical Osteology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.