Clin Osteol 2011; 16(1): 8-10
Diagnosis and treatment of bone disease in chronic kidney patients -osteoporosis or renal osteodystrophy?Short communications
Abnormalities of mineral and bone metabolism develop already in the early stages of chronic kidney disease (CKD) and progress with decline of kidney function. Bone disease may result in fractures, bone pain and deformities in growing children. Fractures occur in 47 % more commonly in elderly patients, in women, in diabetic patients, in those using glucocorticoids and in those with a longer ex posure to dialysis. In CKD patients with advanced decline of renal functions (stages 3-5D), bone disease is characterized as renal os teodystrophy which can only be exactly diagnosed by bone biopsy. Elderly patients with postmenopausal or age related osteoporosis usually have CKD (stages 1, 2 or early stage 3) as well. Both osteoporosis and renal osteodystrophy may result in fractures but the pa thophysiology is different. Therefore, different diagnostic and therapeutic approach should be accepted.
Keywords: chronic kidney disease, renal osteodystrophy, osteoporosis
Published: June 11, 2011 Show citation
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