Clin Osteol 2010; 15(2): 62-67

Nutrition in secondary osteoporosis due to gastrointestinal diseaseReview articles

P. Fojtík, P. Novosad, O. Urban

Secondary osteoporosis is more frequent than expected, with the prevalence of 30-60 % in men and 50 % in perimenopausal women. The most frequent postmenopausal osteoporosis might be combined with secondary osteoporosis and diagnosing and treating these patients might be challenging. The main cause of secondary osteoporosis are gastrointestinal diseases such as inflammatory bowel di­ seases (Crohn's disease, ulcerative colitis), coeliac disease, chronic cholestatic liver disease, gastric and intestinal surgery, pancreatic exocrine insufficiency, lactose intolerance and glucocorticosteroid treatment. Patients with osteoporosis are usually treated by osteo­ logists and patients with gastrointestinal diseases by gastroenterologists. Since these patients have both osteoporosis and digestive di­ sease, the collaboration between gastroenterologists and osteologists is necessary to diagnose and treat these patients properly. Nutrition has a significant impact on bone health throughout life. Proper nutritional status is essential for bone mass growth in child­ hood and adolescence. Moreover, it is necessary for maintaining bone mass during life. An adequate intake of calcium, vitamin D and vitamin K is essential in the treatment of osteoporosis. Recently, the positive effect of vitamin K2 on osteocalcin has been discovered. Additionally, the impact of proteins, omega-3 fatty acids, vitamins and other trace elements on bone metabolism has been confirmed.

Keywords: osteoporosis, secondary osteoporosis, coeliac disease, lactose intolerance, nutrition, vitamin K2

Published: December 11, 2010  Show citation

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Fojtík P, Novosad P, Urban O. Nutrition in secondary osteoporosis due to gastrointestinal disease. Osteologický bulletin. 2010;15(2):62-67.
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