Clin Osteol 2006; 11(4): 104-110

Bone disease in cystic fibrosisReview articles

E. Očenášková, H. Vaníček

With prolonged survival of cystic fibrosis patients, new problems emerged, such as their bone health. Osteoporosis and its complications may increase their morbidity and mortality and negatively influence their life quality. There is a complex of negative contributing factors, especially unfavourable nutritional status, vitamin deficiencies, inflammation, low physical activity, cystic fibrosis related diabetes mellitus, liver disease, hypogonadism and systemic corticosteroids in late stages. Puberty and adolescence are specific risk periods from this point of view. Assessing bone mineral density in CF, body parameters and maturation should be taken into account. Although the frequency of low bone density in CF might be overestimated, preventive measures are necessary already in childhood.

Keywords: Cystic fibrosis, DXA, bone mineral density, osteoporosis, vitamin D, pQCT

Published: December 11, 2006  Show citation

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Očenášková E, Vaníček H. Bone disease in cystic fibrosis. Osteologický bulletin. 2006;11(4):104-110.
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