Prediction of asymptomatic vertebral fractures by selected clinical risk factorsOriginal contributions

Z. Killinger, D. Čierny, P. Jackuliak, M. Kužma, J. Payer

Clin Osteol 2017; 22(1): 3-8

Modern diagnosis of osteoporosis and assessment of fracture risk in girls with Turner syndromeOriginal contributions

O. Souček, J. Lebl, K. Maratová, Z. Šumník

Clin Osteol 2017; 22(1): 9-18

This condition is also associated with osteoporosis and frequent fractures. The aims were to determine volumetric bone mineral density and bone strength, to measure muscle function, to evaluate their relationships and differences from healthy controls, and to test associations with the duration of hormone replacement therapy and the incidence of fractures. Patients, material and methods: Included in the study were 67 (39) girls with Turner syndrome. Volumetric bone mineral density (vBMD) and bone strength parameters at the radius were determined by peripheral quantitative computed tomography (pQCT) and compared with the published reference norms....

Diagnosis and treatment of bone disease in multiple myeloma; II. Treatment of myeloma bone disease in clinical practiceOriginal contributions

V. Ščudla, J. Minařík, T. Pika, P. Krhovská, J. Bačovský

Clin Osteol 2017; 22(1): 19-31

Presented is a current view of the available and prospective possibilities of treating myeloma bone disease (MBD) in cli­ nical practice with emphasis on the key benefit of intravenous therapy with amino-bisphosphonates (BPNs), in particular zoledronic acid (ZA) or pamidronate, in the prevention and treatment of bone-destructive skeletal involveme ple myeloma (MM). Presented are the International Myeloma Working Group and European Myeloma Network guide­ lines summarizing the recent principles of the rational use of BFN, focal radiotherapy, balloon kyphoplasty and surgical treatment which, together with effective anti-MM therapy, reduce bone pain, limit...

Vitamin K and its importance for the vessel wall and bone metabolismReview articles

M. Laburda, K. Vondra, V. Zamrazil, J. Čepová, E. Klapková, K. Dunovská

Clin Osteol 2017; 22(1): 32-37

News from around the worldLiterature

Clin Osteol 2017; 22(1): 38-40