Clin Osteol 2024; 29(4): 128-131

Osteoporosis and liver diseasesReview articles

Koącál Mojmír1,2
1 Interní oddělení - osteocentrum, Oblastní nemocnice Mladá Boleslav, a. s., nemocnice Středočeského kraje
2 Osteologické centrum FN Královké Vinohrady, Praha

Increasing attention to the interaction between liver and bone has stimulated interest in targeted interventions for various forms of osteoporosis. Liver damage induced by various liver diseases can cause imbalances in bone metabolism, suggesting a new regulatory paradigm between liver and bone. However, the role of the liver in the development of osteoporosis is still not well understood. Therefore, investigating the precise regulatory mechanisms (liver-bone) may offer innovative clinical approaches to treat liver and bone-related diseases.

Keywords: liver; liver disease; liver transplantation; osteoporosis; treatment

Published: December 11, 2024  Show citation

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Koącál M. Osteoporosis and liver diseases. Clinical Osteology. 2024;29(4):128-131.
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References

  1. Nuti R, Brandi ML, Checchia G et al. Guidelines for the management of osteoporosis and fragility fractures. Intern Emerg Med 2018; 14(1): 85-102. Dostupné z DOI: <http://dx.doi.org/10.1007/s11739-018-1874-2>. Go to original source...
  2. Burra P, Burroughsy A, Graziadei I et al. [European Association for the Study of the Liver]. EASL Clinical Practice Guidelines: Liver transplantation. J Hepatol 2016; 64(2): 433-485. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jhep.2015.10.006>. Go to original source...
  3. Guanabens N, Pares A. Osteoporosis in chronic liver disease. Liver Int 2018; 38(5): 776-785. Dostupné z DOI: <http://dx.doi.org/10.1111/liv.13730>. Go to original source...
  4. Collier J, Ninkovic M, Compston J. Guidelines on the management of osteoporosis assciated with chronic liver disease. Gut 2002; 50(Suppl 1): i1-i9. Dostupné z DOI: <http://dx.doi.org/10.1136/gut.50.suppl_1.i1>. Go to original source...
  5. Santos LA, Romeiro FG. Diagnosis and Management of Cirrhosis-Related Osteoporosis. Biomed Res Int 2016 : 2016 : 1423462. Dostupné z DOI: <http://dx.doi.org/10.1155/2016/1423462>. Go to original source...
  6. Hirschfield GM, Beuers U, Corpechot C et al. [European Association for the Study of the Liver]. EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. J Hepatol. 2017; 67(1):145-172. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jhep.2017.03.022>. Go to original source...
  7. Merli M, Berzigotti A, Zelber-Sagi S et al. [European Association for the Study of the Liver]. EASL Clinical Practice Guidelines on nutrition in chronic liver disease. J Hepatol 2019; 70(1): 172-193. Dostupné z DOI: <http://dx.doi.org/10.1016/j.jhep.2018.06.024>. Go to original source...
  8. Guss JD, Taylor E, Rouse Z et al. The microbial metagenome and bone tissue composition in mice with microbiome-induced reductions in bone strength. Bone 2019; 127 : 146-154. Dostupné z DOI: <http://dx.doi.org/10.1016/j.bone.2019.06.010>. Go to original source...
  9. Liu JM, Zhao HY, Ning G et al. IGF-1 as an early marker for low bone mass or osteoporosis in premenopausal and postmenopausal women. J Bone Miner Metab 2008; 26(2): 159-164. Dostupné z DOI: <http://dx.doi.org/10.1007/s00774-007-0799-z>. Go to original source...
  10. Bellido T, Saini V, Pajevic PD. Effects of PTH on osteocyte function. Bone 2013; 54(2): 250-257. Dostupné z DOI: <http://dx.doi.org/10.1016/j.bone.2012.09.016>. Go to original source...
  11. Boyce BF, Li P, Yao Z et al. TNF-alpha and pathologic bone resorption. Keio J Med 2005; 54(3): 127-131. Dostupné z DOI: <http://dx.doi.org/10.2302/kjm.54.127>. Go to original source...
  12. Hsu E, Pacifici R. From osteoimmunology to osteomicrobiology: How the microbiota and the immune system regulate bone. Calcif Tissue Int 2018; 102(5): 512-521. Dostupné z DOI: <http://dx.doi.org/10.1007/s00223-017-0321-0>. Go to original source...
  13. Das M, Cronin O, Keohane DM et al. Gut microbiota alterations associated with reduced bone mineral density in older adults. Rheumatology (Oxford) 2019; 58(12): 2295-2304. Dostupné z DOI: <http://dx.doi.org/10.1093/rheumatology/kez302>. Go to original source...
  14. Nilsson AG, Sundh D, Backhed F et al. Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: A randomized, placebo-controlled, double-blind, clinical trial. J Intern Med 2018; 284(3): 307-317. Dostupné z DOI: <http://dx.doi.org/10.1111/joim.12805>. Go to original source...
  15. Lan GB, Xie XB, Peng LK et al. Current status of research on osteoporosis after solid organ transplantation: Pathogenesis and management. Biomed Res Int 2015 : 2015 : 413169. Dostupné z DOI: <http://dx.doi.org/10.1155/2015/413169>. Go to original source...
  16. Loria L, Albanese C, Giusto M et al. Bone disorders in patients with chronic liver disease awaiting liver transplantation. Transplant Proc 2010; 42(4): 1191-1193. Dostupné z DOI: <http://dx.doi.org/10.1016/j.transproceed.2010.03.096>. Go to original source...




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