Clin Osteol 2012; 17(2): 43-49

Surprisingly low bone density in obese patients undergoing bariatric surgeryOriginal contributions

M. Bužga, V. Šmajstrla, L. Bortlík, Z. Švagera, I. Závacká, P. Holéczy

Aim: Low body mass index (BMI) is the major risk factor for osteoporosis. Obesity, on the contrary, is considered to be a protective factor for the skeleton. However, some studies have shown that only moderate overweight and obesity have beneficial effects on the skeleton, while heavy and morbid obesity (BMI over 35, eventually 40 kg/m2) is disadvantageous for the skeleton. The aim of this stu­ dy wa sity.

Material and methods: Ninety-two patients were included in a prospective pilot study on the effects of the gastric sleeve resection of BMD and bone metabolism. We investigated these morbidly obese patients (21 men and 71 women) with two-photon bone densito­ metry (DXA). Pa comorbidities).

Results: The mean BMI of men was 43.66, of women 42.47. All women were premenopausal; patients with possible secondary osteo­ porosis were thereby excluded. The average score of all patients was 1.06 for spine and 1.57 for femur, which is within the normal ran­ ge, eventually slightly above the average. Yet in six patients we found the scores decreased: in four patients from -1 to -2.5 SD (range "osteopenia") and in three even less than -2.5 SD (range "osteoporosis"). The lowest values were found on the spine. One man had ve­ ry low density (Z-score was -4.2 SD). All the six pat en adipose tissue and skeleton is mutual and complex. Discussion and conclusion: Our measurements confirm the protective effect of higher body mass on bone mineral density. Nevertheless, in some individuals with BMI over 40 we found low bone density. The causes for this are still unknown; they may in­ clude the influence of proinflammatory cytokines produc sence of hypovitaminosis D in obese and other factors.

Keywords: adipose tissue, obesity, bone mineral density

Published: December 11, 2012  Show citation

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Bužga M, Šmajstrla V, Bortlík L, Švagera Z, Závacká I, Holéczy P. Surprisingly low bone density in obese patients undergoing bariatric surgery. Osteologický bulletin. 2012;17(2):43-49.
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