Clin Osteol 2006; 11(2-3): 51-56

CalciphylaxisNews

Šenk F.

Calciphylaxis is a rare and for the most part lethal disorder of calcium-phosphate (Ca-P) metabolism. It occurs primarily in patients on dialysis and after kidney transplantation. The pathogenesis of this condition has, as yet, not been unravelled and in consequence all treatment is only symptoma­ tic. It is a necrotic affection of the epidermis and dermis due to an extensive calcinosis of the arteriole media, which often goes hand in hand with a se­ condary infection of these areas and the development of a generalized septic condition - in most instances resulting in the patient's death. The letha­ lity of this disease depends, among other things, on the extent of necrosis, the severity and type of the complicating septic condition and the patient's age and co-morbidity.

Keywords: calciphylaxis, Ca-P metabolism, calcinosis of the artiole media, necrosis of the epidermis and dermis, septic condition Osteologický bulletin 2006;11(2-3):51-56

Published: December 11, 2006  Show citation

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Šenk F. Calciphylaxis. Osteologický bulletin. 2006;11(2-3):51-56.
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    References

    1. Adrogue HJ, Frazier MR, Zeluff B, Suki WN. Systemic calciphylaxis revisited. Am J Nephrol 1981;1:177-183. Go to original source...
    2. Kent RB, Lylerly RT. Systemic calciphylaxis, South Med J 1994;87:278-281. Go to original source...
    3. PerloffLJ, Spence RK, Grossmann RA, Barker CF. Letal post-transplantation cal­ cinosis, Transplantation 1979;27:21-25. Go to original source...
    4. Sulková a kolektiv: Hemodialýza, Maxdorf 2000;462-463.
    5. Ozbalkan Z, Galguneri M, Onat AM, Ozturk MA Development of calciphylaxis after long-term steroid and methotrexate use in a patient with rheumatoid arthri­ tis, Int Medicine Vol. 44, No. 11, Nov. 2005,1178-1181. Go to original source...
    6. Griffith TF, Hartle JE, Quarles LD. UpToDate Calciphylaxis; 1/2002.
    7. Pliquett RU, Schwock J, Paschke R, Achenbach H. Calciphylaxis in chronic, non­ dialysis-dependent renal disease, BMC Nefrol 2003;4:8. Go to original source...
    8. Toprak D, Bircan Z, Gokal AS. Calciphylaxis due to poor compliance in a child with end stage renal disease, Pediatr Int 2005;47,95-98. Go to original source...
    9. Budisavljevic MN, Cheek D, Ploth DW. Calciphylaxis in chronic renal failure, J Am Soc Nephrol 1996;7:978-982. Go to original source...
    10. Selye H, Gabbiani G, Strebel R. Sensitization to calciphylaxis by endogenous pa­ rathyroid hormone, Endocrinology 1962;1:554-558. Go to original source...
    11. Ross CN, Cassidy MJ, Thompson M et al. Proximal cutaneous necrosis associa­ ted with small vesel calcification in renal failure, Q J Med 1991;79:443-450.
    12. Don B, Chin A A strategy for the treatment of calcific uremic arteriolopathy (cal­ ciphylaxis) employing a combination of terapie, Clin Nephrol 2003;59,463-70. Go to original source...
    13. Bardsley S, Coutts R, Wilson C: Calciphylaxis and its surgical significance, ANZ J Surg 2005;75,356-359. Go to original source...
    14. Miller S, Vernon-Roberts E, McClure J. Cutaneous calciphylactic reactions in the mouse and the rat and the effects of disphosphonates on the reaction in the rat, JPthol 1984;142:7-13. Go to original source...
    15. Podymow T, Wherret C, Burns KD. Hyperbaric oxygen int the treatment of cal­ ciphylaxis: a case series, Nephrol Dial Transplant 2001;16:2176-2180. Go to original source...

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