Clin Osteol 2025; 30(1): 36-40
Predikcia osteoporotických zlomenín na základe intenzity signálu MR?Původní práce
- 1 Department of Medical and Technical Disciplines in Health Care, Faculty of Health Care, University of Prešov, Prešov
- 2 Department of Radiology, Trnava University Hospital, Trnava
- 3 Clinic of Radiology, AGEL Košice-Šaca Hospital, Košice-Šaca
- 4 Osteocentre, AGEL Košice-Šaca Hospital, Košice-Šaca
- 5 Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov in Prešov, Prešov
Hyperintenzita pozorovaná na T1 vážených obrazoch (T1vo) magnetickej rezonancie (MR) môže indikovať pokles počtu buniek kostnej drene a zvýšenie obsahu tuku. Okrem parametrov z dvojenergetickej röntgenovej absorpciometrie (dual-energy X-ray absorptiometry, DEXA) bolo našim cieľom v tejto štúdii posúdiť využitie M-skóre z MR pre včasnú detekciu osteoporózy. Piatim novodiagnostikovaným osteoporotickým ženám boli stanovené: hustota kostného tkaniva (bone mass density, BMD), T-skóre a trabekulárne kostné skóre (trabecular bone score, TBS ) v oblasti lumbálnej chrbtice prostredníctvom DEXA, ktoré následne podstúpili MR vyšetrenie za účelom určenia hodnôt pomer signál-šum (signal-to-noise-ratio, SNR) z T1vo pre výpočet M-skóre. Medzi SNR/M-skóre verzus TBS sa zistila pozitívna korelácia a priblíženie sa k štatistickej významnosti pravdepodobne pre nižší počet probandov. Interakcia zobrazovacích metód ponúka predpoklad, žeby sa MR mohla stať neinvazívnou oportúnnou skríningovou modalitou pri diagnostike a skorej liečbe osteoporózy, vrátane včasnej predikcie osteoporotických zlomenín.
Klíčová slova: DEXA, zlomenina, M-skóre, MR, TBS.
Zveřejněno: 1. březen 2025 Zobrazit citaci
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