Clin Osteol 2026; 31(1): 49-52 | DOI: 10.36290/clo.2026.007

Importance of B vitamins for the neuromusculoskeletal systemReview articles

Milan Grofik, Katarína Kramár

Neurologická klinika, Jesseniova lekárska fakulta Univerzity Komenského v Martine, Univerzitná nemocnica Martin

The B vitamins represent a chemically heterogeneous group of eight hydrophilic essential compounds. In the human body, they play an important role as coenzymes in various cellular reactions. The B vitamins have long been known for their irreplaceable role in the proper functioning of the nervous system, but in recent years, scientific knowledge has been increasing supporting their important role in maintaining the physiological functions of the muscular and skeletal systems. They are also necessary for adequate regeneration of damaged musculoskeletal tissues in various disease states. Data from "Evidence-Based Medicine" postulate them as effective adjuvant analgesic therapy, especially in the treatment of musculoskeletal non-specific back pain, where they have the potential to shorten the duration of treatment with non-steroidal anti-inflammatory drugs, thus improving the safety profile of this treatment. The basic prerequisites for effective treatment with B vitamins are a sufficiently high daily dose and an adequate duration of treatment.

Keywords: B vitamins, back pain, sarcopenia, musculoskeletal disorders.

Accepted: March 25, 2026; Published: March 30, 2026  Show citation