Clin Osteol 2026; 31(1): 26-34 | DOI: 10.36290/clo.2026.004

Comprehensive overview of bone disease in oncology patientsMain theme

Beata Špániková

Osteocentrum pre vybrané onkologické diagnózy, Onkologický ústav sv. Alžbety, Bratislava

The issue of bone changes in cancer patients an interesting and important part of supportive care for cancer patients. The incidence of many cancers is increasing, thanks to advances in treatment options, many cancer patients are surviving for a long time. Decrease in bone density is often result of the cancer disease itself and/or adverse event of anticancer therapy. Therefore, solving this problem is of great importance for the quality of life of long-term survivors. In this article we present an overview of the most common skeletal complications, their underlying pathophysiological mechanisms, diagnostic and differential diagnostic and the therapeutic management options. Our Osteocenter for selected oncological diagnoses in OUSA Bratislava celebrates its twentieth anniversary. This is one of the reasons for writing this article as a summary of our results. It can be a solution guide at the same time to the approach to oncological patients at risk of BMD decrease or already developed osteoporosis

Keywords: bone mineral density, cancer, metastases, anticancer treatment, osteocenter.

Accepted: March 25, 2026; Published: March 30, 2026  Show citation